HIO
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HIO may refer to:
- Hillsboro Airport, in Washington County, Oregon, United States
- Hypoiodous acid, an oxidising agent
- Hybrid input-output algorithm, in coherent diffraction imaging
- Oslo University College, the largest state university college in Norway
- Østfold University College, a further and higher education institution in south-eastern Norway
- Tsoa language, spoken in Botswana and Zimbabwe