Jump to content

GRIPAP1

From Wikipedia, the free encyclopedia
(Redirected from GRIPAP1 (gene))
GRIPAP1
Identifiers
AliasesGRIPAP1, GRASP-1, GRIP1 associated protein 1
External IDsOMIM: 300408; MGI: 1859616; HomoloGene: 41348; GeneCards: GRIPAP1; OMA:GRIPAP1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_020137
NM_207672

RefSeq (protein)

NP_064522

Location (UCSC)Chr X: 48.97 – 49 MbChr X: 7.66 – 7.69 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

GRIP1-associated protein 1 is a protein that in humans is encoded by the GRIPAP1 gene.[5][6]

Function

[edit]

GRASP1 is a neuron-specific guanine nucleotide exchange factor for the Ras family of small G proteins (RasGEF) and is associated with the GRIP/AMPA receptor complex in brain (Ye et al., 2000).[supplied by OMIM][6]

Interactions

[edit]

GRIPAP1 has been shown to interact with GRIP1.[5]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000068400Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031153Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b Ye B, Liao D, Zhang X, Zhang P, Dong H, Huganir RL (Aug 2000). "GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex". Neuron. 26 (3): 603–17. doi:10.1016/S0896-6273(00)81198-8. PMID 10896157.
  6. ^ a b "Entrez Gene: GRIPAP1 GRIP1 associated protein 1".

Further reading

[edit]