Fumarylacetoacetic acid

Fumarylacetoacetic acid
Names
	Preferred IUPAC name (2E)-4,6-Dioxooct-2-enedioic acid
Identifiers
CAS Number	28613-33-4 ; 5698-51-1 ;
3D model (JSmol)	Interactive image;
ChemSpider	4444081;
MeSH	Fumarylacetoacetate
PubChem CID	5280398;
UNII	FM3BV7K438 ;
CompTox Dashboard (EPA)	DTXSID20901388 ;
	InChI InChI=1S/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1+ Key: GACSIVHAIFQKTC-OWOJBTEDSA-N; InChI=1/C8H8O6/c9-5(1-2-7(11)12)3-6(10)4-8(13)14/h1-2H,3-4H2,(H,11,12)(H,13,14)/b2-1+ Key: GACSIVHAIFQKTC-OWOJBTEDBU;
	SMILES O=C(\C=C\C(=O)O)CC(=O)CC(=O)O;
Properties
Chemical formula	C8H8O6
Molar mass	200.146 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Fumarylacetoacetic acid (fumarylacetoacetate) is an intermediate in the metabolism of tyrosine. It is formed through the conversion of maleylacetoacetate into fumarylacetoacetate by the enzyme maleylacetoacetate isomerase.^[1]

References

^ W. E. Knox and M. LeMay-Knox (1951). "The oxidation in liver of l-tyrosine to acetoacetate through p-hydroxyphenylpyruvate and homogentisic acid". Biochem. J. 49 (5): 686–693. doi:10.1042/bj0490686. PMC 1197578. PMID 14886367.

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[1] W. E. Knox and M. LeMay-Knox (1951). "The oxidation in liver of l-tyrosine to acetoacetate through p-hydroxyphenylpyruvate and homogentisic acid". Biochem. J. 49 (5): 686–693. doi:10.1042/bj0490686. PMC 1197578. PMID 14886367.

[1]

See also

References