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File:Tubular adenoma 2 high mag.jpg

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Summary

Description
English: High micrograph of a colorectal tubular adenoma without high grade dysplasia. H&E stain.

The lesional tissue, i.e. dysplastic epithelium, is seen on the left of the image and characterized by:

  • Nuclear hyperchromatism (i.e. dark purple nuclei) - that extends to the surface,
  • Nuclear crowding (i.e. nuclei are bunched-up),
  • Elliptical/cigar-shaped nuclei and loss of goblet cells/reduction in the number of goblet cells.

Normal colonic type epithelium is seen on the right of the image and characterized by small round nuclei and abundant goblet cells.

The subtle vertical lines (most notable overlying the neoplastic tissue) are an artifact of the tissue preparation.

The same case:

  • Low mag.
    Low mag.
  • Intermed. mag.
    Intermed. mag.
  • High mag.
    High mag.

Another case:

  • High mag.
    High mag.
Source Own work
Author Nephron

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current01:07, 27 October 2009Thumbnail for version as of 01:07, 27 October 20094,272 × 2,848 (3.27 MB)Nephron{{Information |Description={{en|1=High micrograph of a colorectal '''tubular adenoma''' without high grade dysplasia. H&E stain. The lesional tissue, i.e. dysplastic epithelium, is seen on the left of the

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