File:Topological ramifications of DNA replication and transcription.jpg
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Summary
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English: Topological consequences of DNA metabolism. i) During DNA replication, strand separation leads to positive supercoiling ahead of the advancing protein machinery, and precatenane formation behind. Precatenanes form as the newly-synthesised duplexes wrap around one and other, and, if not removed prior to complete of replication, catenated DNA molecules are formed. ii) During transcription, strand separation leads to positive supercoiling ahead of the advancing protein machinery, and negative supercoil formation behind |
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| Source | Own work |
| Author | Kcneuman |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 06:11, 10 April 2022 | | 2,674 × 1,152 (355 KB) | Kcneuman | Uploaded own work with UploadWizard |
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