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File:Topo IA catalytic cycle Illustration.png

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Summary

Description
English: Strand-passage mechanism for type IA topos. (1) Topo binds the G-segment ssDNA region, (2) the G-segment is cleaved. (3) The topo DNA gate is opened, (4) which allows T-segment transfer through the cleaved G-strand. (5) The DNA gate is closed, (6) and the G-strand is re-ligated, changing the linking number by 1. (7) The topo can then go through another round of relaxation or dissociate from the DNA. Type IA topo (domains 1-4) is in pink, the active site tyrosine is yellow and the DNA is grey.
Date
Source Own work
Author Kcneuman

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Topo IA catalytic cycle Illustration

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10 April 2022

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current06:24, 10 April 2022Thumbnail for version as of 06:24, 10 April 20222,366 × 1,906 (724 KB)KcneumanUploaded own work with UploadWizard

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