English: This diagram represents the seven pillars of aging: macromolecular damage, epigenetics, inflammation, adaptation to stress, proteostasis, stem cells and regeneration, metabolism. The proponents of this concept argue each pillar is highly interconnected with the other pillars.
Date
Source
David Gems & João Pedro de Magalhães (2021) The hoverfly and the wasp: A critique of the hallmarks of aging as a paradigm. Ageing Research Reviews Author manuscript made available via the rights retention strategy; available in PMC from Aug 2nd 2021. Figure 5: https://europepmc.org/articles/PMC7611451/figure/F5/
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Captions
The seven pillars of aging: macromolecular damage, epigenetics, inflammation, adaptation to stress, proteostasis, stem cells and regeneration, metabolism.
Семь столпов старения: макромолекулярные повреждения, эпигенетика, воспаление, адаптация к стрессу, протеостаз, стволовые клетки и регенерация, метаболизм