DescriptionThe Alternating Access Model for UCP1 with H+ as a Substrate.jpg
English: The salt bridges at the cytoplasmic side of the protein close after binding a substrate, in this case H+, sealing the protein off from the inter membrane space. The protein's matrix side salt bridges release and the protein opens to the matrix and releases the substrate.
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The Alternating Access Model for UCP1 with H+ as a Substrate