English: Snf3/Rgt2-singalling pathway. In absence of glucose repressing complex composed of Rgt1, Mth1/Std1, Cyc8 and Tup1 blocks transcription of HXT genes. When glucose (Glu) is present casein kinase is activated and phosphorylates Mth1/Std1 which is subsequently ubiquitinated and degraded by the proteasome allowing transcription to proceed.
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Own work, based on FEMS Microbiology Reviews Vol. 32, 4 Pages: 673-704.
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