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File:Sessile serrated adenoma 3 very high mag.jpg

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Description
English: Very high magnification micrograph of a sessile serrated adenoma, abbreviated SSA, from the cecum removed during a colonoscopy. H&E stain.

SSAs are characterized by:

  • basal dilation of the crypts,
  • basal crypt serration,
  • crypts that run horizontal to the basement membrane (horizontal crypts), and
  • crypt branching.

Unlike traditional colonic adenomas (e.g. tubular adenoma, villous adenoma), they do not typically have nuclear changes (nuclear hyperchromatism, nuclear crowding, elliptical/cigar-shaped nuclei).

SSAs are considered pre-malignant lesions, i.e. precursors to cancer, and tend to be found in the right colon.

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    High mag.
Source Own work
Author Nephron

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current03:45, 18 July 2010Thumbnail for version as of 03:45, 18 July 20102,848 × 4,272 (5.13 MB)Nephron{{Information |Description={{en|1=Very high magnification micrograph of a '''sessile serrated adenoma''', abbreviated '''SSA''', from the cecum removed during a colonoscopy. [[w

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