English: Rituximab mechanisms of action; the three major independent mechanisms are (1) antibody dependent cellular cytotoxicity (ADCC), (2) complement mediated cytotoxicity (CMC), and (3) apoptosis; subset panel illustrates a schematic view of CD20 structure and rituximab.
Seyfizadeh, N., et al., A molecular perspective on rituximab: A monoclonal antibody for B cell non Hodgkin lymphoma and other affections. Critical Reviews in Oncology / Hematology. 97: p. 275-290.
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