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ProteinDesignSearch.gif (200 × 200 pixels, file size: 805 KB, MIME type: image/gif, looped, 120 frames, 1 min 0 s)

Summary

Description
English: This animation illustrates the complexity of a protein design search. A typical protein design search compares all the rotamer-conformations from all possible mutations at all residues. In this example the residues Phe36 and His 106 are allowed to mutate to, respectively, the amino acids Tyr and Asn. Phe and Tyr have 4 rotamers each in the rotamer library, while Asn and His have 7 and 8 rotamers, respectively, in the rotamer library (from the Richardson's penultimate rotamer library) . The animation loops through all (4 + 4) x (7 + 8) = 120 possibilities. The structure shown is that of myoglobin, PDB id: 1mbn.
Date
Source Own work
Author Pablo.gainza

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10 April 2013

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Date/TimeThumbnailDimensionsUserComment
current18:58, 11 April 2013Thumbnail for version as of 18:58, 11 April 2013200 × 200 (805 KB)Pablo.gainzaReduced the resolution to 200x200 pixels
19:14, 10 April 2013Thumbnail for version as of 19:14, 10 April 2013600 × 600 (4.34 MB)Pablo.gainzaUser created page with UploadWizard

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