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Summary

Description
English: The anatomy of glomerular basement membrane and podocyte. Podocyte is the last barrier of the glomerulus filtration membrane, which contains a slit diaphragm with 30–50 nm width. The abundant cytoskeleton proteins, such as actin and synaptopodin, maintain the normal shape of podocytes. The membrane proteins, such as podocalyxin, TRPC6, podocin, and nephrin, played an essential role in the podocyte function. Podocyte anchored into the GBM through integrins and uPAR interaction. TRPC6, transient receptor potential cation channel subfamily C member 6; GBM, glomerular basement membrane; uPAR, urokinase-type plasminogen activator receptor; CD2AP, CD2-associated protein.
Date
Source https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645964/
Author Lijun Yin, Lu Yu, John Cijiang He, and Anqun Chen

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Captions

The anatomy of glomerular basement membrane and podocyte

4 November 2021

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current21:14, 30 January 2024Thumbnail for version as of 21:14, 30 January 2024625 × 574 (149 KB)PecMoUploaded a work by Lijun Yin, Lu Yu, John Cijiang He, and Anqun Chen from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8645964/ with UploadWizard

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