File:Pleuromutilin proposed cyclisation mechanism.png
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Summary
| Description |
English: Proposed biosynthetic pathway of pleuromutilin. The left part of the scheme is representing a general biosynthetic approach for Geranylgeranyl pyrophosphate (GGPP). The follwoing cyclisation steps to the pleuromutilin tricyclic core will be provided by class II and class I terpene synthase domain of Pl-cyc. Final catalytic, stereospecific hydroxylation at C-11 and C-3, regiospecific oxidation of the 3-hydroxy group to a keton, acetyl-group-transfers OH-14 and final hydroxylation at the α-acetyl position will lead to pleuromutilin. |
| Date | |
| Source | Own work |
| Author | Ameisensoldat |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 16:21, 24 May 2021 | | 3,074 × 2,121 (398 KB) | Ameisensoldat | Cross-wiki upload from en.wikipedia.org |
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