Jump to content

File:Pegaptanib induced fit binding.png

Page contents not supported in other languages.
This is a file from the Wikimedia Commons
From Wikipedia, the free encyclopedia

Original file (850 × 340 pixels, file size: 85 KB, MIME type: image/png)

Summary

Description
English: Free aptamer conformation and induced fit binding between the wet AMD treatment Macugen (pegaptanib) and its target, VEGF165, as determined by nuclear magnetic resonance (NMR) spectroscopy. The protein is in yellow. Residues undergoing conformational change on binding are in blue, while the other residues are in orange. Residues participating in binding are highlighted in red. CC BY 4.0 license.
Date
Source Zhang, N., Chen, Z., Liu, D., Jiang, H., Zhang, Z. K., Lu, A., ... & Zhang, G. (2021). Structural biology for the molecular insight between aptamers and target proteins. International Journal of Molecular Sciences, 22(8), 4093. Publisher: MDPI.
Author Ning Zhang, Zihao Chen, Dingdong Liu, Hewen Jiang, Zong-Kang Zhang, Aiping Lu, Bao-Ting Zhang, Yuanyuan Yu, and Ge Zhang

Licensing

w:en:Creative Commons
attribution
This file is licensed under the Creative Commons Attribution 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

Captions

Free aptamer conformation and induced fit binding between Macugen (pegaptanib), a wet AMD drug, and its target protein, VEGF165.

15 April 2021

image/png

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current16:49, 1 July 2022Thumbnail for version as of 16:49, 1 July 2022850 × 340 (85 KB)AllAmericanBreakfast"a" and "b" subfigure identifiers removed
16:38, 1 July 2022Thumbnail for version as of 16:38, 1 July 2022850 × 340 (81 KB)AllAmericanBreakfastUploaded a work by Ning Zhang, Zihao Chen, Dingdong Liu, Hewen Jiang, Zong-Kang Zhang, Aiping Lu, Bao-Ting Zhang, Yuanyuan Yu, and Ge Zhang from Zhang, N., Chen, Z., Liu, D., Jiang, H., Zhang, Z. K., Lu, A., ... & Zhang, G. (2021). Structural biology for the molecular insight between aptamers and target proteins. International Journal of Molecular Sciences, 22(8), 4093. Publisher: MDPI. with UploadWizard

The following page uses this file:

Global file usage

The following other wikis use this file:

Metadata