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File:PARP1 binding olaparib 5DS3.png

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Summary

Description Mixed surface–ribbon representation of the catalytic domain of human poly (ADP-ribose) polymerase 1 (PARP1) binding the small-molecule inhibitor olaparib (shown as a space-filling model). Representation-independent color control was used to color the surface and ribbon diagrams differentially in the interest of clarity.
 
This structure was created with PyMOL.
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Source

From PDB entry 5DS3. More information:

  • Dawicki-McKenna JM, Langelier MF, Denizio JE, et al. PARP-1 activation requires local unfolding of an autoinhibitory domain. Mol Cell. 2015;60(5):755-68. doi:10.1016/j.molcel.2015.10.013
Author Fvasconcellos (talk · contribs)
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11 August 2017

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4110afee596fc8f6e0c9bfc1e325148ac1c06c6a

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Date/TimeThumbnailDimensionsUserComment
current04:54, 11 August 2017Thumbnail for version as of 04:54, 11 August 20171,440 × 1,207 (1.12 MB)Fvasconcellos=={{int:filedesc}}== {{Information |Description=Mixed surface–ribbon representation of the {{w|catalytic domain}} of human {{w|poly (ADP-ribose) polymerase}} 1 ({{w|PARP1}}) binding the small-molecule inhibitor {{w|olaparib}} (shown as a {{w|space-fi...

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