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File:Natalizumab 4IRZ.png

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Summary

Description Space-filling model of the Fab fragment of the monoclonal antibody natalizumab (pink/purple) bound to the headpiece of α4β7-integrin (teal).
Style made to resemble the Protein Data Bank's "Molecule of the Month" series, illustrated by Dr. David S. Goodsell of the Scripps Research Institute. Created using QuteMol (http://qutemol.sourceforge.net). Optimized with OptiPNG.
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Source

From PDB entry 4IRZ. More information:

  • Yu Y, Schürpf T, Springer TA. How natalizumab binds and antagonizes α4 integrins. J Biol Chem. 2013 Nov 8;288(45):32314-25. doi:10.1074/jbc.M113.501668
Author Fvasconcellos (talk · contribs)
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Public domain I, the copyright holder of this work, release this work into the public domain. This applies worldwide.
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8 November 2017

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Date/TimeThumbnailDimensionsUserComment
current05:21, 8 November 2017Thumbnail for version as of 05:21, 8 November 20172,048 × 2,048 (155 KB)Fvasconcellos=={{int:filedesc}}== {{Information |Description={{w|Space-filling model}} of the {{w|Fragment antigen-binding|Fab fragment}} of the {{w|monoclonal antibody}} {{w|natalizumab}} (pink/purple) bound to the headpiece of α4β7-integrin (tea...

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