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English: EM image and the overall structure of grouper nervous necrosis virus (GNNV). (A) A representative negative-staining EM image of the purified GNNV-LPs after self-assembly. (B) A ribbon presentation of the subunit C of GNNV-LP. The disordered N-ARM (residue 1−33, gray), N-arm (residues 34−51, magenta), the S-domain (residues 52−213, red), the linker region (residues 214−220, blue), the P-domain (residues 221−338, cyan) and Ca2+ ion (yellow sphere) are shown. (C) A topology diagram of GNNV CP with the helices and strands in cylinders and arrows, respectively. The 1D topology of the subunit C is color-coded as in B. (D) Surface domain-colored diagram (left) and central cavity (right) representations of the T = 3 GNNV-LP. The tip-to-tip distance is ~350 Å, the diameter of the central cavity is ~228 Å, and the spike protrusion on the capsid surface is ~47 Å. The S-domains of the subunits A, B and C are shown in orange, blue and red, respectively, and the P-domains are shown in cyan. The structure of the GNNV-LP is viewed along the I2, I3 and I5 axes.
Date
Source Chen N-C, Yoshimura M, Guan H-H, Wang T-Y, Misumi Y, Lin C-C, et al. (2015) Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection. PLoS Pathog 11(10): e1005203. https://doi.org/10.1371/journal.ppat.1005203 (Fig. 1)
Author Nai-Chi Chen, Masato Yoshimura, Hong-Hsiang Guan, Ting-Yu Wang, Yuko Misumi, Chien-Chih Lin, Phimonphan Chuankhayan, Atsushi Nakagawa, Sunney I. Chan, Tomitake Tsukihara, Tzong-Yueh Chen, Chun-Jung Chen
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EM image and the overall structure of grouper nervous necrosis virus (GNNV).

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22 October 2015

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current11:58, 6 December 2020Thumbnail for version as of 11:58, 6 December 20202,221 × 2,015 (3.61 MB)Guest2625Uploaded a work by Nai-Chi Chen, Masato Yoshimura, Hong-Hsiang Guan, Ting-Yu Wang, Yuko Misumi, Chien-Chih Lin, Phimonphan Chuankhayan, Atsushi Nakagawa, Sunney I. Chan, Tomitake Tsukihara, Tzong-Yueh Chen, Chun-Jung Chen from Chen N-C, Yoshimura M, Guan H-H, Wang T-Y, Misumi Y, Lin C-C, et al. (2015) Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection. PLoS Pathog 11(10): e1005203. https://doi.org/10.1371/journal.ppat.1005203 with UploadWizard

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