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Summary

Description Space-filling model of the Fab fragment of the monoclonal antibody isatuximab (pale blue), as bound to CD38 (purple).
Style made to resemble the Protein Data Bank's "Molecule of the Month" series, illustrated by Dr. David S. Goodsell of the Scripps Research Institute. Created using QuteMol (http://qutemol.sourceforge.net) and GIMP. Optimized with OptiPNG.
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From PDB entry 4CMH. More information:

  • Deckert J, Wetzel MC, Bartle LM, Skaletskaya A, Goldmacher VS, Vallée F et al. (September 2014). "SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic malignancies". Clin Cancer Res 20 (17): 4574–83. DOI:10.1158/1078-0432.CCR-14-0695. PMID 24987056.
Author Fvasconcellos (talk · contribs)
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26 October 2020

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Date/TimeThumbnailDimensionsUserComment
current14:38, 26 October 2020Thumbnail for version as of 14:38, 26 October 20201,829 × 1,829 (137 KB)Fvasconcellos=={{int:filedesc}}== {{Information |Description={{w|Space-filling model}} of the {{w|Fragment antigen-binding|Fab fragment}} of the {{w|monoclonal antibody}} {{w|isatuximab}} (pale blue), as bound to {{w|CD38}} (purple).<br>Style made to resemble the {{w|Protein Data Bank}}'s "Molecule of the Month" series, illustrated by Dr. David S. Goodsell of {{w|the Scripps Research Institute}}. Created using {{w|QuteMol}} (http://qutemol.sourceforge.net) and {{w|GIMP}}. Optimized with {{w|OptiPNG}}. |So...

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