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File:Interneuron-radial glial interactions in the developing cerebral cortex.png

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Interneuron-radial_glial_interactions_in_the_developing_cerebral_cortex.png (425 × 600 pixels, file size: 83 KB, MIME type: image/png)

Description
English: Interneurons (green) migrating into the cerebral wall from the ganglionic eminence(GE) interact with radial glia (red) and can exhibit changes in direction of migration after contacting radial glia. Interneurons can use radial glia as a scaffold upon which to migrate as they ascend to the cortical plate (CP) or descend in the direction of the ventricular zone (VZ). Particular orientation and morphological dynamics of migration may be associated with particular subsets of interneurons. Once the interneurons invade the cortex from the ganglionic eminence, differential interactions between interneurons and radial glial scaffold and localized multidirectional migration of interneurons influenced by local guidance cues may facilitate interneuronal positioning within distinct domains of the developing cerebral cortex. Potential differences among interneurons and radial glia are indicated by shades of green and red, respectively. Putative local guidance cues are indicated by a gradient of pink. Blue arrows indicate direction of migration.
Date
Source Yokota Y, Ghashghaei HT, Han C, Watson H, Campbell KJ, et al. (2007) Radial Glial Dependent and Independent Dynamics of Interneuronal Migration in the Developing Cerebral Cortex. PLoS ONE 2(8): e794. doi:10.1371/journal.pone.0000794
Author Yukako Yokota1, H. T. Ghashghaei1¤, Christine Han, Hannah Watson, Kenneth J. Campbell, E.S. Anton
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current12:41, 21 August 2009Thumbnail for version as of 12:41, 21 August 2009425 × 600 (83 KB)CopperKettle{{Information |Description={{en|1=Interneurons (green) migrating into the cerebral wall from the ganglionic eminence(GE) interact with radial glia (red) and can exhibit changes in direction of migration after contacting radial glia. Interneurons can use r

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