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English: The designer cytokine Hyper-IL-6 is a fusion protein of the soluble Interleukin-6 receptor and Interleukin-6 covalently connected by a 40 Å flexible peptide linker. Hyper-IL-6 was 100-1000 times more active than the combination of the separate proteins Interleukin-6 and soluble Interleukin-6 receptor. A, B, C, D, helices of Interleukin-6; D-II, D-III, domains of the soluble Interleukin-6 receptor, which form the so-called cytokine binding module.
Date
Source Own work
Author SRJ6

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9 June 2020

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current10:09, 9 June 2020Thumbnail for version as of 10:09, 9 June 2020720 × 405 (32 KB)SRJ6Cross-wiki upload from en.wikipedia.org

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