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File:Histopathology of tall cell and hobnail variants of papillary thyroid carcinoma.jpg

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Summary

Description
English: Columnar cell variant of papillary thyroid carcinoma (PTC) showing a combination of papillary and glandular-like patterns (a), marked nuclear pseudostratification, and less nuclear features of classic PTC (b). In the tall cell variant of PTC, the cytoplasm is deeply eosinophilic, and nuclear features of PTC are very prominent with irregular contours and common pseudoinclusions (c). Hobnail variant of PTC combining papillary (d), and micropapillary (e) structures lined by hobnail cells. “Teardrop” cells (f) and comet-like cells (inset). The cribriform-morular thyroid carcinoma exhibits a blending of cribriform, papillary, trabecular, and solid pattern with morules (g) and (h). Morules are strongly positive for CD10 (i). Tumor cells are reactive for estrogen receptors (j), and there is strong nuclear and cytoplasmic reactivity for β-catenin (k)
Date
Source Cameselle-Teijeiro JM, Eloy C, Sobrinho-Simões M (2020). "Pitfalls in Challenging Thyroid Tumors: Emphasis on Differential Diagnosis and Ancillary Biomarkers.". Endocr Pathol 31 (3): 197-217. DOI:10.1007/s12022-020-09638-x. PMID 32632840. PMC: 7395918.
"This article is licensed under a Creative Commons Attribution 4.0 International License"
Author José Manuel Cameselle-Teijeiro & Catarina Eloy & Manuel Sobrinho-Simões

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Histopathology of tall cell and hobnail variants of papillary thyroid carcinoma

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6 June 2020

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Date/TimeThumbnailDimensionsUserComment
current17:37, 7 April 2022Thumbnail for version as of 17:37, 7 April 20221,527 × 1,772 (1.1 MB)Mikael HäggströmUploaded a work by José Manuel Cameselle-Teijeiro & Catarina Eloy & Manuel Sobrinho-Simões from {{cite journal| author=Cameselle-Teijeiro JM, Eloy C, Sobrinho-Simões M| title=Pitfalls in Challenging Thyroid Tumors: Emphasis on Differential Diagnosis and Ancillary Biomarkers. | journal=Endocr Pathol | year= 2020 | volume= 31 | issue= 3 | pages= 197-217 | pmid=32632840 | doi=10.1007/s12022-020-09638-x | pmc=7395918 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=s...

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