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File:High grade serous carcinoma theories of origin diagram.png

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English: Top half depicts how a stem cell in the ovarian surface epithelium may become enclosed in the ovary during ovulation and form part of a cortical inclusion cyst (CIC). This cyst may then undergo Mullerian metaplasia followed by malignant transformation into a Type I tumour (i.e. one that has a precursor). Alternatively the CIC may simply undergo malignant transformation and develop into a Type II tumour (such as HGSC) de novo. Lower half of image describes how a fimbrial stem cell (or insome cases a serous tubal intraepithelial carcinoma) may become enclosed in the ovary during ovulation and form part of a cortical inclusion cyst that can undergo malignant transformation into a Type II tumour.
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Author Ainenicaomh

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3 September 2016

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Date/TimeThumbnailDimensionsUserComment
current18:30, 25 September 2016Thumbnail for version as of 18:30, 25 September 20161,711 × 1,158 (554 KB)CmdrjamesonCompressed with pngout. Reduced by 337kB (37% decrease).
19:38, 8 September 2016Thumbnail for version as of 19:38, 8 September 20161,711 × 1,158 (892 KB)AinenicaomhUser created page with UploadWizard

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