File:Glucoregulatory hyperbola.png
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Summary
| Description |
English: Hyberbolic relationship between insulin sensitivity and beta cell function showing dynamical compensation in "healthy" insulin resistance (transition from A to B) and the evolution of type 2 diabetes mellitus (transition from A to C). Inspired by Cobelli et al. 2007 (Cobelli, C; Toffolo, GM; Dalla Man, C; Campioni, M; Denti, P; Caumo, A; Butler, P; Rizza, R (July 2007). "Assessment of beta-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose tests". American journal of physiology. Endocrinology and metabolism. 293 (1): E1–E15. doi:10.1152/ajpendo.00421.2006. PMID 17341552) and Hannon et al. 2018 (Hannon, TS; Kahn, SE; Utzschneider, KM; Buchanan, TA; Nadeau, KJ; Zeitler, PS; Ehrmann, DA; Arslanian, SA; Caprio, S; Edelstein, SL; Savage, PJ; Mather, KJ; RISE, Consortium (January 2018). "Review of methods for measuring β-cell function: Design considerations from the Restoring Insulin Secretion (RISE) Consortium". Diabetes, obesity & metabolism. 20 (1): 14–24. doi:10.1111/dom.13005. PMID 28493515)
Deutsch: Hyperbolischer Zusammenhang zwischen Insulinsensitivität und Betazellfunktion. Dynamische Kompensation bei "gesunder" Insulinresistenz ist durch den Übergang von A nach B, die Entwicklung eines Diabetes mellitus Typ 2 durch den Übergang von A nach C gekennzeichnet. Auf der Grundlage von Cobelli et al. 2007 (Cobelli, C; Toffolo, GM; Dalla Man, C; Campioni, M; Denti, P; Caumo, A; Butler, P; Rizza, R (July 2007). "Assessment of beta-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose tests". American journal of physiology. Endocrinology and metabolism. 293 (1): E1–E15. doi:10.1152/ajpendo.00421.2006. PMID 17341552) und Hannon et al. 2018 (Hannon, TS; Kahn, SE; Utzschneider, KM; Buchanan, TA; Nadeau, KJ; Zeitler, PS; Ehrmann, DA; Arslanian, SA; Caprio, S; Edelstein, SL; Savage, PJ; Mather, KJ; RISE, Consortium (January 2018). "Review of methods for measuring β-cell function: Design considerations from the Restoring Insulin Secretion (RISE) Consortium". Diabetes, obesity & metabolism. 20 (1): 14–24. doi:10.1111/dom.13005. PMID 28493515) |
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| Source | Own work |
| Author | Jwdietrich2 |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 20:33, 2 March 2023 | | 1,500 × 1,500 (122 KB) | Jwdietrich2 | Uploaded own work with UploadWizard |
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