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Summary

Description The nutriepigenetic pathway of maternal choline-deficient diets helps to elucidate the development of fetal alcohol syndrome. Pregnant rodents fed diets low in choline were found to give rise to offspring with diminished neurological capacity. This is similar to pregnant rodents whom were fed ethanol and were found to have alterations in the metabolism of 1-carbon compounds. This leads to diminished levels of methyl donors available for methylating DNA; thus allowing for overexpression of normally silenced genes causing neurological defects in their offspring.
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Author KShaw KKowalec

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17 February 2011

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Date/TimeThumbnailDimensionsUserComment
current06:44, 18 February 2011Thumbnail for version as of 06:44, 18 February 2011800 × 600 (52 KB)KShaw KKowalec{{Information |Description=The nutriepigenetic pathway of maternal choline-deficient diets helps to elucidate the development of fetal alcohol syndrome. Pregnant rodents fed diets low in choline were found to give rise to offspring with diminished neurol

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