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File:Estradiol and testosterone levels with high-dose estradiol patches in men.png

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Summary

Description
English: Estradiol and testosterone levels with two to six 7.8-mg 100 µg/day estradiol transdermal patches per week in men with prostate cancer.

"Six transdermal estradiol (7.8 mg.) patches were applied weekly for 8 weeks and then the number of patches was reduced to maintain castrate levels of testosterone." "Hormone responses (mean trough levels using 2 (7.8 mg.) estradiol patches a week to maintain castrate (less than 2 nmol./l. testosterone). Two patches a week were sufficient to maintain castrate testosterone but were changed twice weekly to boost trough estradiol levels, and maintain patch adhesion and patient compliance."

This excerpt and source indicates that the patches used in the study provided a dosage of estradiol of 100 µg/day (the original publication did not specify this): "Available information suggests that for preparations delivering 100 µg/day of oestradiol transdermally (including the Progynova [TS forte] patches used in the original pilot study [5]) [...]":

A review that reproduced the graph from the original publication:

  • (October 2006). "Therapy Insight: parenteral estrogen treatment for prostate cancer--a new dawn for an old therapy". Nat Clin Pract Oncol 3 (10): 552–63. DOI:10.1038/ncponc0602. PMID 17019433.
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Created from source material using WebPlotDigitizer and Plotly.

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Author Medgirl131 at English Wikipedia

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The person who associated a work with this deed has dedicated the work to the public domain by waiving all of their rights to the work worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law. You can copy, modify, distribute and perform the work, even for commercial purposes, all without asking permission.

Original upload log

The original description page was here. All following user names refer to en.wikipedia.
Date/Time Dimensions User Comment
2018-07-03 13:47 2206×1375× (139637 bytes) Medgirl131 Fix right y-axis zero line -> light gray to black.
2018-01-04 16:02 2206×1375× (141951 bytes) Medgirl131 == Summary == I made this, anyone can use it. Created from source material using [https://automeris.io/WebPlotDigitizer/ WebPlotDigitizer] and [https://plot.ly/ Plotly]. Estradiol and testosterone levels with two to six 7.8-mg estradiol transdermal pa...

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Date/TimeThumbnailDimensionsUserComment
current03:04, 18 January 2021Thumbnail for version as of 03:04, 18 January 20212,688 × 1,679 (263 KB)Vanished user 0x8cSXE0x6Fix right Y-axis line bottom.
03:01, 18 January 2021Thumbnail for version as of 03:01, 18 January 20212,715 × 1,670 (282 KB)Vanished user 0x8cSXE0x6X-axis in original wasn't linear scale... fixed.
05:20, 17 June 2019Thumbnail for version as of 05:20, 17 June 20191,853 × 1,104 (267 KB)Vanished user 0x8cSXE0x6A few more improvements.
05:15, 17 June 2019Thumbnail for version as of 05:15, 17 June 20191,854 × 1,094 (288 KB)Vanished user 0x8cSXE0x6Improvements.
00:30, 7 September 2018Thumbnail for version as of 00:30, 7 September 20182,206 × 1,375 (136 KB)OgreBot(BOT): Reverting to most recent version before archival
00:30, 7 September 2018Thumbnail for version as of 00:30, 7 September 20182,206 × 1,375 (139 KB)OgreBot(BOT): Uploading old version of file from en.wikipedia; originally uploaded on 2018-01-04 16:02:23 by Medgirl131
01:41, 6 September 2018Thumbnail for version as of 01:41, 6 September 20182,206 × 1,375 (136 KB)Vanished user 0x8cSXE0x6Transferred from en.wikipedia via #commonshelper