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File:Engineered Nucleases.jpg

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Various categories of engineered nucleases currently used for genome editing. ZFN (zinc finger nuclease) and TALEN (Transcription activator-like effector nuclease) are linked to the active catalytic domains of FokI endonuclease. FokI subunits can be engineered to function as heterodimers only to increase specificity. Naturally occurring meganucleases can be engineered into hybrids to cover greater sequence diversity.

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Powerpoint
Previously published: No

Date

March 1st, 2012

Author

Farzad Jamshidi

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current01:21, 2 March 2012Thumbnail for version as of 01:21, 2 March 2012756 × 735 (231 KB)Seahorsechipmunk (talk | contribs)Uploading a self-made file using File Upload Wizard

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