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Summary

Description
English: Diagnostic algorithm of suspected Cushing's syndrome:
ACTH=adrenocorticotropic hormone.
CBG=corticosteroid-binding globulin
CRH=corticotropin-releasing hormone
DST=dexamethasone suppression test.
IPSS=inferior petrosal sinus sampling
UFC=urinary free cortisol.
*There is consensus that all patients with lesions smaller than 6 mm in diameter should have IPSS and those with lesions of ≥10 mm do not need IPSS, but expert opinions differed for lesions 6–9 mm in diameter
†This alternative option does not have clear consensus and needs further research, and this is indicated by darker boxes.
Green boxes indiate points to consider
Darker colors indicate less validated testing pathways.
Date
Source Fleseriu M, Auchus R, Bancos I, Ben-Shlomo A, Bertherat J, Biermasz NR (2021). "Consensus on diagnosis and management of Cushing's disease: a guideline update.". Lancet Diabetes Endocrinol 9 (12): 847-875. DOI:10.1016/S2213-8587(21)00235-7. PMID 34687601. PMC: 8743006.
Author Fleseriu M, Auchus R, Bancos I, Ben-Shlomo A, Bertherat J, Biermasz NR

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Public domain This chart is ineligible for copyright and therefore in the public domain, because it consists entirely of information that is common property and contains no original authorship. For more information, see Commons:Threshold of originality § Charts

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Diagnostic algorithm of suspected Cushing's syndrome.

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20 October 2021

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Date/TimeThumbnailDimensionsUserComment
current13:10, 27 June 2023Thumbnail for version as of 13:10, 27 June 20232,213 × 2,627 (190 KB)Mikael HäggströmUploaded a work by Fleseriu M, Auchus R, Bancos I, Ben-Shlomo A, Bertherat J, Biermasz NR from {{cite journal| author=Fleseriu M, Auchus R, Bancos I, Ben-Shlomo A, Bertherat J, Biermasz NR | display-authors=etal| title=Consensus on diagnosis and management of Cushing's disease: a guideline update. | journal=Lancet Diabetes Endocrinol | year= 2021 | volume= 9 | issue= 12 | pages= 847-875 | pmid=34687601 | doi=10.1016/S2213-8587(21)00235-7 | pmc=8743006 | url=https://www.ncbi.nlm.nih.gov/entrez...

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