File:DXM metabolism.png
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Summary
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English: Main metabolism pathways for dextromethorphan degeration catalyzed by cytochrome P450 monooxygenases (CYP3A4 and CYP2D6) and UDP-glucuronosyl-transferase (UGT).
Source: Katja Strauch, Ursula Lutz, Nataly Bittner, Werner K. Lutz: Dose-response relationship for the pharmacokinetic interaction of grapefruit juice with dextromethorphan investigated by human urinary metabolite profiles. Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association, August 2009, nro 8, s. 1928–1935. PubMed:19445995. doi:10.1016/j.fct.2009.05.004. ISSN 1873-6351.Suomi: Pääasialiset metaboliset reitit dextrometorfaanin hajoamiselle, joita katalysoivat sytokromi P450 mono-oksigenaasit (CYP3A4 ja CYP2D6) ja UDP-glukuronyylitransferaasi (UGT).
Lähde: Katja Strauch, Ursula Lutz, Nataly Bittner, Werner K. Lutz: Dose-response relationship for the pharmacokinetic interaction of grapefruit juice with dextromethorphan investigated by human urinary metabolite profiles. Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association, August 2009, nro 8, s. 1928–1935. PubMed:19445995. doi:10.1016/j.fct.2009.05.004. ISSN 1873-6351. |
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| Source | Own work |
| Author | Keministi |
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| current | 22:53, 24 March 2018 | | 886 × 1,199 (13 KB) | 5-HT2AR | User created page with UploadWizard |
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