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English: Comparing uptake of RNA and modRNA by the cell: (Left) modRNA delivery does not cause any activation of immune response and escapes RNase degradation. (Right) mRNA triggers activation of TLR7/8 and is prone to degradation by RNase.
Date
Source mRNA-Based Protein Replacement Therapy for the Heart. Molecular Therapy 27 (4): 785–793. doi:10.1016/j.ymthe.2018.11.018
Author Ajit Magadum, Keerat Kaur, Lior Zangi
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Comparing uptake of RNA and modRNA by the cell

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4 December 2018

image/jpeg

e8e2119d9d19550e937cb09eb9f28da225533d56

1,257,682 byte

1,677 pixel

3,362 pixel

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Date/TimeThumbnailDimensionsUserComment
current15:44, 22 December 2020Thumbnail for version as of 15:44, 22 December 20203,362 × 1,677 (1.2 MB)MaxxLhi res
09:29, 13 December 2020Thumbnail for version as of 09:29, 13 December 2020747 × 373 (333 KB)GnomUploaded a work by Ajit Magadum, Keerat Kaur, Lior Zangi from [https://www.sciencedirect.com/science/article/pii/S1525001618305847 mRNA-Based Protein Replacement Therapy for the Heart] with UploadWizard

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