CCPRCC classically has apical nuclei, i.e. the nucleus is adjacent to the luminal aspect.[2]
In most glandular structures the nuclei are usually basally located, i.e. in the cytoplasm adjacent to the basement membrane.
They typically stain with CK7 and do not stain with TFE3 and AMACR.[1]
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High mag.
Very high mag.
References
↑ ab (Sep 2011). "Clear-cell papillary renal cell carcinoma: molecular and immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins.". Mod Pathol24 (9): 1207-20. DOI:10.1038/modpathol.2011.80.
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