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English: a, Tomographic slice of a cardiac sarcomere M-band depicting thick and thin filaments. Scale bar, 50 nm. b, Reconstructed thick and thin filaments mapped into a tomogram. Thin filaments obstructing the view on the thick filament were removed for clarity. Scale bar, 50 nm c, Structure of the thick filament from the M-band to the C-zone. For clarity, only the first four cMyBP-C stripes are shown here. d, Illustration of the various sarcomere components and their color code which is maintained throughout the manuscript, unless otherwise indicated. TM, tropomyosin. TK domain, titin kinase domain.
Date
Source In situ structures from relaxed cardiac myofibrils reveal the organization of the muscle thick filament. https://doi.org/10.1101/2023.04.11.536387
Author Davide Tamborrini, Zhexin Wang, Thorsten Wagner, Sebastian Tacke, Markus Stabrin, Michael Grange, Ay Lin Kho, Martin Rees, Pauline Bennett, Mathias Gautel, Stefan Raunser

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11 April 2023

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current08:56, 7 January 2024Thumbnail for version as of 08:56, 7 January 2024838 × 1,142 (334 KB)NiashervinUploaded a work by Davide Tamborrini, Zhexin Wang, Thorsten Wagner, Sebastian Tacke, Markus Stabrin, Michael Grange, Ay Lin Kho, Martin Rees, Pauline Bennett, Mathias Gautel, Stefan Raunser from https://doi.org/10.1101/2023.04.11.536387 with UploadWizard

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