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File:CNS myelin sheath formation.svg

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Summary

Description
English: Process of myelin sheath formation in the central nervous system.[1][2]
  • 1: Extension of initiator/pioneer process along axon
  • 2: Lamellar extension around axon's circumference to form first turn of myelin sheath
  • 3-5: Circumferential wrapping, lateral growth, and compaction of myelin sheath membrane
  • 6: Mature myelin sheath constituting one internode
Date
Source Own work
Author Aeffenberger

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  1. ↑ Snaidero N, Möbius W, Czopka T, Hekking LH, Mathisen C, Verkleij D (2014). "Myelin membrane wrapping of CNS axons by PI(3,4,5)P3-dependent polarized growth at the inner tongue". Cell 156 (1-2): 277-90. DOI:10.1016/j.cell.2013.11.044. PMID 24439382. PMC: 4862569.
  2. ↑ Hardy RJ, Friedrich VL (1996). "Progressive remodeling of the oligodendrocyte process arbor during myelinogenesis". Dev Neurosci 18 (4): 243-54. DOI:10.1159/000111414. PMID 8911764.

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myelin sheath

oligodendrocyte

axon

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18 October 2021

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