File:CCDC188.png
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Summary
| Description |
English: Topology of CCDC188 located in the ER membrane. The N-terminal basic leucine zipper (blue) and nuclear localization signal (yellow) are located in the cytosol while the C-terminus is located in the ER lumen. A nonsense mutation seen in retinitis pigmentosa is located just downstream of the nuclear localization signal meaning that the mutated protein product contains no transmembrane domain but still has a nuclear localization signal to direct it to the nucleus. |
| Date | |
| Source | Own work |
| Author | Janibas24 |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 15:18, 7 December 2021 | | 1,466 × 1,414 (808 KB) | Janibas24 | Cross-wiki upload from en.wikipedia.org |
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