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File:Application of mukaiyama hydration in the total synthesis of (±)-Garsubellin A.svg

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Application of mukaiyama hydration in the total synthesis of (±)-Garsubellin A as reported in J. Am. Chem. Soc. (2005) 127, 14200–14201

The hydration reaction is catalyzed by Co(acac)2 (acac = 2,4-pentanedionato, better known as acetylacetonato) and carried out in the presence of air oxygen & phenylsilane.

With isopropanol used as solvent, yields of 73 % are obtained.
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Author Chem Sim 2001
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current16:45, 28 September 2020Thumbnail for version as of 16:45, 28 September 20201,053 × 272 (41 KB)Chem Sim 2001corrected the structures to fit MOS style

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