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File:Antibody basic unit.svg

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Summary

Description
English: Schematic diagram of an antibody (immunoglobulin).

It consists of two heavy chains (blue, yellow) and two light chains (green, pink). One of the two antigen-binding regions is circled: they are formed by the variable regions at the tip of the antibody. The heavy chains have (starting from the N-terminus at the tip) a variable domain (VH), followed by a constant domain (CH1), a hinge region, and two more constant domain (CH2, CH3). The light chains have a variable domain (VL) and a constant domain (CL).

The CH2 and CH3 regions form the crystallizable fragment (Fc). The variable and CH1, CL regions form a pair of antigen-binding fragments (Fab).

Disulfide bonds between the chains are drawn as S-S. Their exact number and location varies for different isotypes.
Date
Source Own work, based on File:Immunoglobulin basic unit.svg by Y_tambe
Author Tokenzero

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Captions

Diagram of an antibody basic unit

Items portrayed in this file

depicts

antibody

inception

3 September 2020

media type

image/svg+xml

checksum

05b1a400185022090d762d05969a76ee238f81f4

determination method or standard: SHA-1

data size

15,734 byte

height

440 pixel

width

506 pixel

File history

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Date/TimeThumbnailDimensionsUserComment
current22:30, 1 November 2020Thumbnail for version as of 22:30, 1 November 2020506 × 440 (15 KB)Tokenzerofix green
22:06, 1 November 2020Thumbnail for version as of 22:06, 1 November 2020506 × 440 (15 KB)Tokenzerosynchronize colors with another image
21:18, 1 November 2020Thumbnail for version as of 21:18, 1 November 2020506 × 440 (15 KB)Tokenzeroimprove font specification, letter spacing, color contrast and use more color-blind-friendly hues
11:18, 3 September 2020Thumbnail for version as of 11:18, 3 September 2020506 × 440 (10 KB)Tokenzeroround corners, improve padding
10:36, 3 September 2020Thumbnail for version as of 10:36, 3 September 2020506 × 440 (9 KB)TokenzeroUploaded own work with UploadWizard

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