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File:Anderson’s diastereoselective nitro-Mannich reaction.svg

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English: Anderson’s diastereoselective nitro-Mannich reaction using nBuLi and AcOH.

Reagents and conditions: i) nBuLi, THF, –78 °C then N-PMB imine 36 then AcOH, –78 °C

to 0 °C; ii) SmI2, THF/MeOH; iii) CAN, MeCN/H2O. Scheme 9, from page 26 of the PDF. The Development of Nitro-Mannich/Hydroamination Cascades for the Synthesis of Substituted N-Heterocycles, PhD thesis.
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Source https://ora.ox.ac.uk/objects/uuid:18e7c533-3789-4800-9813-1d5c7bb4e4ea
Author David Michael Barber

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current19:03, 9 July 2021Thumbnail for version as of 19:03, 9 July 2021429 × 162 (152 KB)MinihaaRemoved numeration of molecules.
19:00, 4 July 2021Thumbnail for version as of 19:00, 4 July 2021429 × 172 (168 KB)MinihaaUploaded a work by David Michael Barber from https://ora.ox.ac.uk/objects/uuid:18e7c533-3789-4800-9813-1d5c7bb4e4ea with UploadWizard

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