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Summary

Description
English: Protease cuts the N-terminal sequence of PAR that exposes a new N-terminal sequence functions as a tethered ligand, which bind a conserved region on extracellular loop 2 (ECL2). Such bound causes the specific change in conformation of the PAR and alters the affinity for intracellular G-protein.
Date
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Author Marta Šlaufová

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Signal transduction by activation of PAR

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5 February 2020

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e9156b18e5cff086b6967f2126d7c9c1e664761e

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908 pixel

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current15:20, 5 February 2020Thumbnail for version as of 15:20, 5 February 2020908 × 370 (24 KB)Marta ŠlaufováUser created page with UploadWizard

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