File:991 activator binding to AMPK Fig2b.gif
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Summary
| Description |
English: "CD titration of 20 μM α1β1γ1 with 991 (0–32 μM). The spectrum of the protein (red) is very different from the spectrum of AMPK:991 complex (blue). Analysing the signal change at 306 nm as a function of 991 concentration (inset—1:1 binding model) gave a Kd of 0.078±0.026 μM." Figure 2b from B.Xiao et al. "Structural basis of AMPK regulation by small molecule activators" Nature Communications 4 doi:10.1038/ncomms4017 . Image and description copied under CC-BY 3.0 licence. |
| Date | |
| Source | http://www.nature.com/ncomms/2013/131219/ncomms4017/full/ncomms4017.html |
| Author | Bing Xiao, Matthew J. Sanders, David Carmena, Nicola J. Bright, Lesley F. Haire, Elizabeth Underwood, Bhakti R. Patel, Richard B. Heath, Philip A. Walker, Stefan Hallen, Fabrizio Giordanetto, Stephen R. Martin, David Carling & Steven J. Gamblin |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 15:54, 14 November 2014 | | 945 × 851 (30 KB) | MartinPoulter | User created page with UploadWizard |
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