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English: Three concentric layers constituted by VP2 and VP5 (outer capsid), VP7 (intermediate layer), and VP3 (subcore) characterized bluetongue virus (BTV) virions (~90 nm in diameter). The RNA polymerase complex, which is located inside the inner capsid, is composed by structural proteins VP1, VP4, and VP6. Five additional proteins (NS1, NS2, NS3/NS3A, NS4, and NS5) are synthesized inside the cell during the replicative cycle. VP2 and NS1 proteins of BTV are expressed by the recombinant MVAs.
Date
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Calvo-Pinilla, E., Marín-López, A., Moreno, S. et al. A protective bivalent vaccine against Rift Valley fever and bluetongue. npj Vaccines 5, 70 (2020).

https://doi.org/10.1038/s41541-020-00218-y
Author Eva Calvo-Pinilla, Alejandro Marín-López, Sandra Moreno, Gema Lorenzo, Sergio Utrilla-Trigo, Luis Jiménez-Cabello, Julio Benavides, Aitor Nogales, Rafael Blasco, Alejandro Brun, and Javier Ortego

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Captions

Three concentric layers constituted by VP2 and VP5 (outer capsid), VP7 (intermediate layer), and VP3 (subcore) characterized bluetongue virus (BTV) virions (~90 nm in diameter).

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30 July 2020

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current08:15, 27 January 2021Thumbnail for version as of 08:15, 27 January 2021885 × 966 (549 KB)Guest2625Uploaded a work by Eva Calvo-Pinilla, Alejandro Marín-López, Sandra Moreno, Gema Lorenzo, Sergio Utrilla-Trigo, Luis Jiménez-Cabello, Julio Benavides, Aitor Nogales, Rafael Blasco, Alejandro Brun, and Javier Ortego from Calvo-Pinilla, E., Marín-López, A., Moreno, S. et al. A protective bivalent vaccine against Rift Valley fever and bluetongue. npj Vaccines 5, 70 (2020). https://doi.org/10.1038/s41541-020-00218-y with UploadWizard

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