English: The human protein phosphatase 2A (PP2A) heterotrimeric complex, shown with the regulatory subunit A (red), regulatory subunit B56 (green), and catalytic subunit (dark blue). Compare File:2pf4 pp2a stag.png to see the SV40 polyomavirus small tumor antigen (STag) binding site on the A subunit; this interaction occludes the binding of the B subunit and thereby inactivates the enzyme.
Rendered from PDB ID 2IAE:
Nature. 2007 Jan 4;445(7123):53-7. Epub 2006 Nov 1.
Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme.
Cho US, Xu W.
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