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Elazer R. Edelman

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Elazer Edelman
EducationMassachusetts Institute of Technology (BS, MS, PhD)
Harvard University (MD)
Known forAtherosclerotic arterial disease, vascular biology, drug delivery
Children3, including Alex and Adam Edelman
Scientific career
FieldsBiomedical Engineering
Cardiology
Vascular Biology
InstitutionsMassachusetts Institute of Technology
Harvard Medical School
Brigham and Women's Hospital
Doctoral advisorRobert S. Langer
Other academic advisorsMorris Karnovsky

Elazer R. Edelman is an American engineer, scientist and cardiologist. He is the Edward J. Poitras Professor in Medical Engineering and Science at the Massachusetts Institute of Technology (MIT), Professor of Medicine at Harvard Medical School and at Brigham and Women's Hospital (BWH), and a practicing cardiologist at BWH.[1][2] He is the director of the MIT Center for Clinical and Translational Research (CCTR),[3] the Harvard-MIT Biomedical Engineering Center,[4] and was previously director of the Institute for Medical Engineering and Science (IMES) at MIT.[5] He is also the Program Director of the MIT Graduate Education in Medical Sciences program within the Harvard-MIT Division of Health Sciences and Technology.[6][7]

At BWH, he serves as a senior attending physician in the coronary care unit. He is currently the Chief Scientific Advisor for the journal Science Translational Medicine.[8]

Edelman was elected as a member of the National Academy of Engineering in 2012 for contributions to the design, development, and regulation of local cardiovascular drug delivery and drug eluting stents. He is also a member of the American Academy of Arts and Sciences, National Academy of Inventors and the National Academy of Medicine.[9][10][11][12]

Background and education

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Edelman was raised in the greater Boston area. He attended the Massachusetts Institute of Technology, where he received bachelor's degrees in Electrical Engineering and Computer Science (EECS) and in Applied Biology, and a master's degree in EECS. He earned his M.D. degree with distinction from Harvard Medical School and Ph.D. in Medical Engineering and Medical Physics within the Harvard-MIT Division of Health Sciences and Technology. He conducted his Ph.D. thesis work under the direction of Robert Langer to define the mathematics of regulated and controlled drug delivery. Edelman completed his medical training at Brigham and Women's Hospital and is board certified in internal medicine and cardiology. Following this, he spent six years as a research fellow under the tutelage of Prof. Morris J. Karnovsky to work on the biology of vascular repair.[13] Edelman and his wife, Cheryl, have 3 children: Alex, A.J., and Austin.

Research

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Edelman is a major advocate of multidisciplinary research.[14][15] Through his research centers, he combines teams of clinicians, engineers, and scientists from both academia and industry to create highly effective and clinically relevant solutions to medical problems.[16] Through this approach, Edelman and his students have been credited as some of the key contributors and pioneers of the coronary stent. They critically aided in the development, characterization, and optimization of the first bare-metal stents and subsequent iterations including drug-eluting stents.[17][18] Edelman's research programs fall in the following general categories:[13]

  • polymer-based controlled and modulated drug delivery
  • vascular biology, glycobiology, and growth factor biochemistry
  • tissue engineering
  • biomaterials and tissue interactions
  • device biology

Awards and honors

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Edelman has authored or co-authored more than 680 original scientific publications, holds some 80 patents, and has trained more than 300 students and post-doctoral fellows. He has served on several advisory boards including the Science Board to the Food and Drug Administration.[13][19]

Edelman has been elected a fellow of the Association of American Physicians, American College of Cardiology, American Heart Association, American Institute for Medical and Biological Engineering, American Society of Clinical Investigators, American Society of Mechanical Engineers, Association of University Cardiologists, American Academy of Arts and Sciences, National Academy of Engineering, National Academy of Medicine, and National Academy of Inventors. He received the Officer's Cross of the Spanish Order of Civil Merit in 2010.[20]

Selected awards received by Edelman include:

Personal life

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Edelman is married to Cheryl, a real estate lawyer,[32] and lives in Brookline, Massachusetts. He has three sons, Austin, Israeli Olympian Adam Edelman, and comedian Alex Edelman.

References

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  1. ^ "Edelman - Institute for Medical Engineering & Science". Institute for Medical Engineering and Science at MIT. Retrieved January 12, 2016.
  2. ^ "BWH Physician Directory". Brigham and Women's Hospital. Retrieved January 12, 2016.
  3. ^ "People". Center for Clinical and Translational Research. December 6, 2021. Retrieved October 11, 2024.
  4. ^ "Edelman Lab – Harvard-MIT Biomedical Engineering Center". Retrieved October 11, 2024.
  5. ^ "Alex Shalek named director of the Institute for Medical Engineering and Science". MIT News | Massachusetts Institute of Technology. August 9, 2024. Retrieved October 11, 2024.
  6. ^ "Elazer Edelman edelmanlab". Harvard-MIT Biomedical Engineering Center. Retrieved January 12, 2016.
  7. ^ "HST to Offer New Medical Program". The Tech. Retrieved January 12, 2016.
  8. ^ "Editorial staff and scientific advisory boards". Science. Retrieved January 12, 2016.
  9. ^ "Alphabetical List of Active Members" (PDF). American Academy of Arts and Sciences. Retrieved February 19, 2016.
  10. ^ "Current NAI Fellows". National Academy of Inventors. Retrieved February 19, 2016.
  11. ^ "Elazer Edelman - National Academy of Engineering Directory". National Academy of Engineering. Retrieved January 12, 2016.
  12. ^ "Elazer Edelman - Institute of Medicine Profile". National Academy of Medicine. Retrieved January 12, 2016.[permanent dead link‍]
  13. ^ a b c d e f g "Elazer Edelman - Curriculum Vitae" (PDF). Elazer Edelman. Archived from the original (PDF) on March 5, 2016. Retrieved January 12, 2016.
  14. ^ "Elazer Edelman - How Do We Bridge the Gap in Medical Innovation?". TEDMED. Retrieved February 19, 2016.
  15. ^ "Elazer Edelman - TEDMED Q&A". TEDMED. Retrieved February 19, 2016.
  16. ^ "Taking many forms of expertise to heart". MIT News. December 9, 2015. Retrieved January 12, 2016.
  17. ^ Hwang, CW; Wu D; Edelman ER (2001). "Physiological transport forces govern drug distribution for stent-based delivery". Circulation. 104 (5): 600–605. doi:10.1161/hc3101.092214. PMID 11479260.
  18. ^ Hwang CW, Levin AD, Jonas M, Li PH, Edelman ER (2005). "Thrombosis modulates arterial drug distribution for drug-eluting stents". Circulation. 111 (13): 1619–26. doi:10.1161/01.CIR.0000160363.30639.37. PMID 15795325.
  19. ^ "Elazer Edelman Bibliography" (PDF). Elazer Edelman. Archived from the original (PDF) on March 6, 2016. Retrieved January 12, 2016.
  20. ^ a b "HST's Edelman receives award from Spanish government". MIT News. June 22, 2010. Retrieved January 12, 2016.
  21. ^ "2018 Distinguished Awardees". ACC. Retrieved January 29, 2019.
  22. ^ "Elazer Edelman honored with Cardiovascular Research Foundation career achievement award". MIT News. October 13, 2017. Retrieved October 16, 2017.
  23. ^ "Bioengineering in Ireland 22". Royal Academy of Medicine in Ireland. Archived from the original on March 1, 2016. Retrieved February 19, 2016.
  24. ^ "Discovery Lecture Series - 2015 Speakers". Vanderbilt University Medical Center. Retrieved February 19, 2016.
  25. ^ "Dean's Distinguished Lecture Series". Weill Cornell Medical College. Retrieved February 19, 2016.
  26. ^ "Awards, Honors, & Grants". Brigham and Women's Hospital. Retrieved January 12, 2016.
  27. ^ "Past Awardees". Society for Biomaterials. Retrieved January 12, 2016.
  28. ^ "Awards, Honors, & Grants". Brigham and Women's Hospital. Retrieved February 19, 2016.
  29. ^ "Jeffrey M. Hoeg Award for Basic Science & Clinical Research". American Heart Association. Archived from the original on September 15, 2015. Retrieved January 12, 2016.
  30. ^ "Excellence in Mentoring Awards Past Recipients". HMS. Retrieved January 12, 2016.
  31. ^ "Awards and Recipients Database". ASTM. Retrieved January 12, 2016.
  32. ^ vCard. "Cheryl Edelman | DLA Piper". www.dlapiper.com. Retrieved July 13, 2024.
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