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Margarita del Val

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Margarita del Val
Born1959 (age 64–65)
SpouseEnrique J. de la Rosa
Academic background
Alma materAutonomous University of Madrid
Doctoral advisorEladio Viñuela Díaz [es]
Academic work
InstitutionsSpanish National Research Council, Severo Ochoa Molecular Biology Centre [es]

Margarita del Val Latorre (born 1959) is a Spanish chemist, immunologist, and virologist. She coordinates the Salud Global ("Global Health") platform run by the Spanish National Research Council (CSIC).

Early life and education

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Margarita del Val was born in Madrid in 1959 to the chemists Manuel del Val and Consuelo Latorre.[1][2] del Val attended the Autonomous University of Madrid (UAM) starting in 1976, during the Transition.[3] During this time, increasing protests on university grounds against the Francoist dictatorship culminated in all Spanish universities going on strike starting in 1973,[4] which was ongoing when she arrived at the university.[1] In the absence of any classes, del Val and other students read books and played games.[3] One book she read described how proteins were made in cells, which influenced her decision to study biochemistry and she completed her thesis in 1985 under the supervision of Eladio Viñuela Díaz [es].[5]

Career

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In the 1980s, del Val began working at the Severo Ochoa Molecular Biology Centre [es], a research institute at the UAM jointly run by the university and the CSIC.[1][better source needed] After completing her doctorate in 1986, she left for West Germany, spending two years at the Federal Research Centre for Virus Diseases of Animals in Tübingen, a now-defunct research institution of the Friedrich Loeffler Institute.[6] She then spent three years at the University of Ulm. del Val returned to Spain in the 1990s, having developed an experimental vaccine design based on isolated T-cell epitopes.[1] Afterwards, del Val stayed abroad at the National Institutes of Health in Bethesda, Maryland and McGill University in Montreal, before spending twenty years at the Carlos III Health Institute.[year needed]

In April 2020, del Val helped set up and launch the Salud Global ("Global Health") program, a CSIC project facilitating COVID-19 research between over 300 Spanish research groups.[1][7] del Val has provided her thoughts on Spain's experience with the COVID-19 pandemic[8][2] and requested an investigation into Spain's handling of the pandemic.[9]

Selected publications

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  • Saveanu, Loredana; Carroll, Oliver; Lindo, Vivian; Del Val, Margarita; Lopez, Daniel; Lepelletier, Yves; Greer, Fiona; Schomburg, Lutz; Fruci, Doriana; Niedermann, Gabriele; van Endert, Peter M. (2005). "Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum". Nature Immunology. 6 (7): 689–697. doi:10.1038/ni1208. ISSN 1529-2916. PMID 15908954. S2CID 31585869.
  • Val, Margarita Del; Schlicht, Hans-Jürgen; Ruppert, Thomas; Reddehase, Matthias J.; Koszinowski, Ulrich H. (20 September 1991). "Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein". Cell. 66 (6): 1145–1153. doi:10.1016/0092-8674(91)90037-Y. ISSN 0092-8674. PMID 1913805. S2CID 24252836.
  • del Val, M; Hengel, H; Häcker, H; Hartlaub, U; Ruppert, T; Lucin, P; Koszinowski, U H (1 September 1992). "Cytomegalovirus prevents antigen presentation by blocking the transport of peptide-loaded major histocompatibility complex class I molecules into the medial-Golgi compartment". Journal of Experimental Medicine. 176 (3): 729–738. doi:10.1084/jem.176.3.729. ISSN 0022-1007. PMC 2119349. PMID 1324970.

Awards and honors

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In 2015 del Val was named a corresponding academician of the Royal Academy of Pharmacy.[10] In 2021 she received the "Medalla de Honor a los Valores Sociales" from Menéndez Pelayo International University for her work in Spain during the COVID-19 pandemic.[11]

Personal life

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del Val is married to the biologist Enrique J. de la Rosa, who she met at the UAM in 1977.[1][2] She has a son and daughter.[3]

References

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  1. ^ a b c d e Casal, Luis (25 November 2020). "Quién es Margarita del Val, la viróloga implacable que alerta sobre la Navidad y desmonta a Simón". El Español. Archived from the original on 22 January 2021. Retrieved 21 January 2021.
  2. ^ a b c Sánchez-Mellado, Luz (20 September 2020). "Margarita del Val: "Me avergüenza el rifirrafe político sobre el virus. ¿Cómo pueden ser tan cortos de vista?"". El País. Archived from the original on 22 January 2021. Retrieved 21 January 2021.
  3. ^ a b c Abad, Ana Fernández (20 November 2020). "Margarita del Val: "Que todo lo malo sea que no vamos a poder celebrar la comida de Navidad. Es un mal menor"". S Moda. El País. Archived from the original on 22 January 2021. Retrieved 21 January 2021.
  4. ^ Carr, Raymond; Aizpurúa, Juan Pablo Fusi (1979). Spain, dictatorship to democracy. London: Allen & Unwin. pp. 148–149. ISBN 0049460129.
  5. ^ Del Val Latorre, Margarita (1985). Componentes glicosilados del virus de la peste porcina africana - Dialnet. Dialnet (Thesis). Archived from the original on 11 June 2020. Retrieved 21 January 2021.
  6. ^ "FLI Tübingen: Friedrich-Loeffler-Institut". Friedrich Loeffler Institute. Archived from the original on 22 January 2021. Retrieved 22 January 2021.
  7. ^ Jar, Núria (23 December 2020). "Margarita del Val, sobre el futuro de la COVID: "Prefiero estar preparada para varios años y que luego sea más corto"". elDiario.es. Archived from the original on 22 January 2021. Retrieved 21 January 2021.
  8. ^ Esteban, Felix (23 July 2021). "¿Por qué Margarita del Val es tan pesimista con la pandemia?". Moncloa (in Spanish). Retrieved 24 March 2022.
  9. ^ Galán, Lola (13 February 2021). "Margarita del Val, la viróloga que entra en los hogares". El País (in Spanish). Retrieved 24 March 2022.
  10. ^ "Toma de posesión como Académica Correspondiente del Ilma. Sra. Dña. Margarita del Val Latorre – Real Academia Nacional de Farmacia". ranf.com. 24 September 2015. Retrieved 24 March 2022.
  11. ^ "La UIMP concede la 'Medalla de Honor a los Valores Sociales' a la viróloga e inmunóloga Margarita del Val - UIMP". www.uimp.es. 18 March 2021. Retrieved 24 March 2022.
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