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Arthur Weston (scientist)

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Emeritus Professor
Arthur Weston
FMedSci FBPhS HonFBPhS
Born
Arthur Henry Weston

(1944-05-31) 31 May 1944 (age 80)
Hull, United Kingdom
CitizenshipUnited Kingdom
Alma materUniversity of Manchester (BSc, MSc, PhD, DSc)
Known forThe discovery and characterisation of potassium channel openers (KCOs)
Children2
AwardsRodolfo Paoletti Medal (2015).[1]

HonFBPhS (2012)[1]

Gaddum Medal (2008)[1]

FBPhS (2004)[1]

FMedSci (2001)[1]

Humboldt Fellowship (1974-75; 1985)[1]
Scientific career
InstitutionsUniversity of Manchester, University of Marburg, University of Heidelberg, Kyushu University, Magdalen College, Oxford

Arthur Henry Weston FMedSci FBPhS HonFBPhS is emeritus professor at the University of Manchester, where he was previously Leech Professor of Pharmacology from 1989-2011.[2]

Early life and education

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Weston was born in 1944 in Cottingham, son of Arthur Edward Weston and Betty Nutt Weston (née Wetherell).[3] He won a Scholarship to Hymers College, Hull in 1955 and entered the Victoria University of Manchester in 1962.[4] After graduating BSc in Pharmacy with First Class Honours in Pharmacology (1966), he obtained his MSc (1968) and PhD (1970).[5]

Career and research

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Weston was made lecturer in pharmacology at Manchester in 1970, senior lecturer in 1979, reader in 1987 and professor in 1989.[6] In 1974, he was awarded an Alexander von Humboldt Fellowship to study in the Department of Physiology in the University of Marburg and a senior Humboldt Fellowship to study in the Department of Physiology in the University of Heidelberg in 1985. During 1987, he was a Royal Society-funded visiting professor in the Department of Pharmacology, University of Kyushu, Japan. In 2011, Weston became a visiting fellow at Magdalen College, Oxford. At a national level, he was honorary treasurer, a director and trustee of the British Pharmacological Society (BPS) for the 8 years from 1999-2008.[7]

Weston's research focuses on the physiology and pharmacology of ion channels in blood vessels and on the development of drugs to treat vascular disease associated with hypertension, diabetes and obesity. During the 1980s he discovered a new class of agent which he designated the "potassium channel opener"[8] and this has formed the basis of many on-going research programmes within the pharmaceutical industry. These studies led to the further discovery that blood vessels produce a relaxing factor that he termed "endothelium-derived hyperpolarizing factor" (EDHF).[9] His most recent discoveries in Manchester concern the existence and role of a special calcium-sensing receptor in the endothelium of blood vessels.[10]

Awards and honours

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In 2001, Weston was elected Fellow of the Academy of Medical Sciences (FMedSci)[11] and in 2004 to a Fellowship of the British Pharmacological Society (FBPhS).[12] At the IUPHAR Meeting in Beijing in July 2006, he was elected President of EPHAR, the Federation of European Pharmacological Societies. In 2008, he was made Honorary Member of the Finnish Pharmacological Society and awarded the Gaddum Medal by the British Pharmacological Society.[13] At the 2010 WorldPharma Meeting in Copenhagen, Weston was presented with a special commemorative award and plaque for his services to European pharmacology, and in 2014 he was awarded the Rodolfo Paoletti Medal by EPHAR[14]

Personal life

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Weston married Dr. Kathleen Margaret (née Goodison) in 1967 and they have two children, Sophie (b. 1970) and Matthew (b. 1972).[15] Weston is an enthusiastic gardener and active member of the Royal Horticultural Society, where he has served on the Crocosmia Annual General Meeting (AGM) Forum and is currently serving on the Geum and Helenium AGM Trials Committees.[16]

References

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  1. ^ a b c d e f "https://www.bps.ac.uk/about/who-we-are/honorary-fellows-directory/professor-arthur-weston/01ff56b2-d7f6-e311-88a7-001dd8b721a7"
  2. ^ "Professor Arthur Weston | The Academy of Medical Sciences". acmedsci.ac.uk. Retrieved 2022-10-17.
  3. ^ "Weston, Prof. Arthur Henry, (born 31 May 1944), Leech Professor of Pharmacology, University of Manchester, 1990–2011, now Emeritus". WHO'S WHO & WHO WAS WHO. 2007. doi:10.1093/ww/9780199540884.013.U43701. ISBN 978-0-19-954088-4. Retrieved 2022-12-02.
  4. ^ "Weston, Prof. Arthur Henry, (born 31 May 1944), Leech Professor of Pharmacology, University of Manchester, 1990–2011, now Emeritus". WHO'S WHO & WHO WAS WHO. 2007. doi:10.1093/ww/9780199540884.013.U43701. ISBN 978-0-19-954088-4. Retrieved 2022-12-02.
  5. ^ "Weston, Prof. Arthur Henry, (born 31 May 1944), Leech Professor of Pharmacology, University of Manchester, 1990–2011, now Emeritus". WHO'S WHO & WHO WAS WHO. 2007. doi:10.1093/ww/9780199540884.013.U43701. ISBN 978-0-19-954088-4. Retrieved 2022-12-02.
  6. ^ "Weston, Prof. Arthur Henry, (born 31 May 1944), Leech Professor of Pharmacology, University of Manchester, 1990–2011, now Emeritus". WHO'S WHO & WHO WAS WHO. 2007. doi:10.1093/ww/9780199540884.013.U43701. ISBN 978-0-19-954088-4. Retrieved 2022-12-02.
  7. ^ "Weston, Prof. Arthur Henry, (born 31 May 1944), Leech Professor of Pharmacology, University of Manchester, 1990–2011, now Emeritus". WHO'S WHO & WHO WAS WHO. 2007. doi:10.1093/ww/9780199540884.013.U43701. ISBN 978-0-19-954088-4. Retrieved 2022-12-02.
  8. ^ Duty, Susan; Weston, Arthur H. (1990-12-01). "Potassium Channel Openers". Drugs. 40 (6): 785–791. doi:10.2165/00003495-199040060-00002. ISSN 1179-1950. PMID 2078995. S2CID 46956574.
  9. ^ Busse, Rudi; Edwards, Gillian; Félétou, Michel; Fleming, Ingrid; Vanhoutte, Paul M.; Weston, Arthur H. (2002-08-01). "EDHF: bringing the concepts together". Trends in Pharmacological Sciences. 23 (8): 374–380. doi:10.1016/S0165-6147(02)02050-3. ISSN 0165-6147. PMID 12377579.
  10. ^ Weston, A. H.; Geraghty, A.; Egner, I.; Edwards, G. (September 2011). "The vascular extracellular calcium-sensing receptor: an update: Ca2+-sensing in the vasculature". Acta Physiologica. 203 (1): 127–137. doi:10.1111/j.1748-1716.2010.02249.x. PMID 21199402. S2CID 43461632.
  11. ^ "Professor Arthur Weston | The Academy of Medical Sciences". acmedsci.ac.uk. Retrieved 2022-10-19.
  12. ^ British Pharmacological Society. "Professor Arthur Weston FMedSci DSc".
  13. ^ British Pharmacological Society. "Gaddum International Lecture Past winners".
  14. ^ "EPHAR - The Federation of European Pharmacological Societies". www.ephar.org. Retrieved 2022-10-19.
  15. ^ "Weston, Prof. Arthur Henry, (born 31 May 1944), Leech Professor of Pharmacology, University of Manchester, 1990–2011, now Emeritus". WHO'S WHO & WHO WAS WHO. 2007. doi:10.1093/ww/9780199540884.013.U43701. ISBN 978-0-19-954088-4. Retrieved 2022-12-02.
  16. ^ "View the Royal Horticultural Society's plant trials and awards / RHS Gardening". www.rhs.org.uk. Retrieved 2022-10-19.
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