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Dammarenediol II synthase

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Dammarenediol II synthase
Identifiers
EC no.4.2.1.125
CAS no.189354-84-5
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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NCBIproteins

Dammarenediol II synthase (EC 4.2.1.125, dammarenediol synthase, 2,3-oxidosqualene (20S)-dammarenediol cyclase, DDS, (S)-squalene-2,3-epoxide hydro-lyase (dammarenediol-II forming)) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (dammarenediol-II forming).[1][2] This enzyme catalyses the following chemical reaction

dammarenediol II (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O

The reaction occurs in the reverse direction.

References

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  1. ^ Tansakul P, Shibuya M, Kushiro T, Ebizuka Y (October 2006). "Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng". FEBS Letters. 580 (22): 5143–9. doi:10.1016/j.febslet.2006.08.044. PMID 16962103.
  2. ^ Han JY, Kwon YS, Yang DC, Jung YR, Choi YE (December 2006). "Expression and RNA interference-induced silencing of the dammarenediol synthase gene in Panax ginseng". Plant & Cell Physiology. 47 (12): 1653–62. doi:10.1093/pcp/pcl032. PMID 17088293.
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