Jump to content

DNAI7

From Wikipedia, the free encyclopedia
(Redirected from Cancer susceptibility 1)
DNAI7
Identifiers
AliasesDNAI7, LAS1, PPP1R54, cancer susceptibility candidate 1, cancer susceptibility 1, cilia and flagella associated protein 94, CASC1, dynein axonemal intermediate chain 7, CFAP94
External IDsOMIM: 616906; MGI: 2444480; HomoloGene: 41242; GeneCards: DNAI7; OMA:DNAI7 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_177222

RefSeq (protein)

NP_796196

Location (UCSC)Chr 12: 25.11 – 25.2 MbChr 6: 145.12 – 145.16 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Dynein axonemal intermediate chain 7 is a protein that in humans is encoded by the DNAI7 gene, also sometimes known as LAS1; CASC1; CFAP94; or PPP1R54. The protein is sometimes referred to as cancer susceptibility 1.[5]

Casc1, alias Las1, is one of the six genes constituting the mouse Pulmonary adenoma susceptibility 1 (Pas1) locus haplotype.[6]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000118307Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043541Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Cancer susceptibility 1". Retrieved 2018-07-16.
  6. ^ Manenti G, Galbiati F, Giannì-Barrera R, Pettinicchio A, Acevedo A, Dragani TA. Haplotype sharing suggests that a genomic segment containing six genes accounts for the pulmonary adenoma susceptibility 1 (Pas1) locus activity in mice. Oncogene. 2004;23(25):4495–4504.

Further reading

[edit]