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CYP197 family

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Cytochrome P450, family 197, also known as CYP197, is a cytochrome P450 monooxygenase family.[1] The first gene identified in this family is the CYP197A1 from Bacillus halodurans.[2] CYP197 is one of the only three P450 families shared in bacteria and archaea, the other two are CYP147 and CYP109.[1] Genes in this family are co-present on archaeal plasmids and chromosomes, implying the plasmid-mediated horizontal gene transfer of these genes from bacteria to archaea.[1]

References

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  1. ^ a b c Ngcobo, PE; Nkosi, BVZ; Chen, W; Nelson, DR; Syed, K (19 February 2023). "Evolution of Cytochrome P450 Enzymes and Their Redox Partners in Archaea". International Journal of Molecular Sciences. 24 (4): 4161. doi:10.3390/ijms24044161. PMC 9962201. PMID 36835573.
  2. ^ Girhard M, Klaus T, Khatri Y, Bernhardt R, Urlacher VB (June 2010). "Characterization of the versatile monooxygenase CYP109B1 from Bacillus subtilis". Applied Microbiology and Biotechnology. 87 (2): 595–607. doi:10.1007/s00253-010-2472-z. PMID 20186410. S2CID 26265331.


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