Valencene synthase
(Redirected from CVS (enzyme))
| Valencene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.73 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Valencene synthase (EC 4.2.3.73) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (valencene-forming).[1] It is a terpene cyclase enzyme responsible for the biosynthesis of valencene, a sesquiterpene, using farnesyl pyrophosphate as its substrate. The first such enzyme was isolated using orange cDNA.[2] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate (+)-valencene + diphosphate
The recombinant enzyme from Vitis vinifera forms (+)-valencene and (-)-7-epi-α-selinene.
References
[edit]- ^ Lücker J, Bowen P, Bohlmann J (October 2004). "Vitis vinifera terpenoid cyclases: functional identification of two sesquiterpene synthase cDNAs encoding (+)-valencene synthase and (-)-germacrene D synthase and expression of mono- and sesquiterpene synthases in grapevine flowers and berries". Phytochemistry. 65 (19): 2649–59. doi:10.1016/j.phytochem.2004.08.017. PMID 15464152.
- ^ Sharon-Asa L, Shalit M, Frydman A, Bar E, Holland D, Or E, et al. (December 2003). "Citrus fruit flavor and aroma biosynthesis: isolation, functional characterization, and developmental regulation of Cstps1, a key gene in the production of the sesquiterpene aroma compound valencene". The Plant Journal. 36 (5). Blackwell Publishing Ltd.: 664–74. doi:10.1046/j.1365-313x.2003.01910.x. PMID 14617067.
External links
[edit]- Valencene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
