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CTNNBL1

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CTNNBL1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCTNNBL1, C20orf33, NAP, P14L, PP8304, dJ633O20.1, catenin beta like 1, IMD99
External IDsOMIM: 611537; MGI: 1913892; HomoloGene: 12003; GeneCards: CTNNBL1; OMA:CTNNBL1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001281495
NM_030877

NM_025680

RefSeq (protein)

NP_001268424
NP_110517

NP_079956

Location (UCSC)Chr 20: 37.69 – 37.87 MbChr 2: 157.58 – 157.73 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Beta-catenin-like protein 1 is a protein that in humans is encoded by the CTNNBL1 gene.[5][6]

The protein encoded by this gene contains an acidic domain, a putative bipartite nuclear localization signal, a nuclear export signal, a leucine-isoleucine zipper, and phosphorylation motifs. In addition, the encoded protein contains Armadillo/beta-catenin-like repeats, which have been implicated in protein-protein interactions. Although the function of this protein has not been determined, the C-terminal portion of the protein has been shown to possess apoptosis-inducing activity.[6] It is a housekeeping gene.

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000132792Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000027649Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Jabbour L, Welter JF, Kollar J, Hering TM (Mar 2003). "Sequence, gene structure, and expression pattern of CTNNBL1, a minor-class intron-containing gene--evidence for a role in apoptosis". Genomics. 81 (3): 292–303. doi:10.1016/S0888-7543(02)00038-1. PMID 12659813.
  6. ^ a b "Entrez Gene: CTNNBL1 catenin, beta like 1".
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Further reading

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