Girolline

Girolline
Names
	IUPAC name (1S,2S)-3-Amino-1-(2-amino-1H-imidazol-5-yl)-2-chloropropan-1-ol
	Other names Giracodazole
Identifiers
CAS Number	110883-46-0 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL1171272;
ChemSpider	59320;
PubChem CID	65911;
UNII	RU19QYB9WZ;
CompTox Dashboard (EPA)	DTXSID80891413 ;
	InChI InChI=1S/C6H11ClN4O/c7-3(1-8)5(12)4-2-10-6(9)11-4/h2-3,5,12H,1,8H2,(H3,9,10,11)/t3-,5+/m0/s1 Key: YILCGOCHVFQMTC-WVZVXSGGSA-N;
	SMILES [C@H]([C@H](CN)Cl)(O)C=1NC(N)=NC1;
Properties
Chemical formula	C6H11ClN4O
Molar mass	190.63 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Girolline (also known as giracodazole) is a chemical compound isolated from a marine sponge. It inhibits protein synthesis.^[1]

Referencess

^ Fung, S. Y.; Sofiyev, V.; Schneiderman, J.; Hirschfeld, A. F.; Victor, R. E.; Woods, K.; Piotrowski, J. S.; Deshpande, R.; Li, S. C.; De Voogd, N. J.; Myers, C. L.; Boone, C.; Andersen, R. J.; Turvey, S. E. (2014). "Unbiased Screening of Marine Sponge Extracts for Anti-inflammatory Agents Combined with Chemical Genomics Identifies Girolline as an Inhibitor of Protein Synthesis". ACS Chemical Biology. 9 (1): 247–257. doi:10.1021/cb400740c. PMC 4371607. PMID 24117378.

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